Cuatro amigos que regentan un pequeño bar en un barrio del sur de Philadelphia, la ciudad del amor fraternal, intentan mantener el equilibrio entre negocio y amistad, tarea nada fácil, ya que cada uno de ellos suele dejarse llevar únicamente por sus intereses personales, lo que desemboca en situaciones incómodas que amenazan con deteriorar sus relaciones personales.
When Psycho Pete, long lost member of the freight train, is released from the mental hospital, Dennis and Dee rush to get him recommitted while Charlie and Mac attempt to restore him to his former hard-partying form.
Charlie goes into overdrive when he's notified that the health inspector will be arriving that day. Meanwhile, the rest of the gang is trying to exploit a flaw in the air-miles reward system.