Sucede en el vecindario ficticio de Manzanares. La serie trata sobre la vida de cuatro amas de casa, siguiendo sus diarios problemas maritales y los misterios que rodean a sus maridos, amigos y vecinos.
El último episodio:may. 13, 2012
(temporada de películas 8, el episodio 23)
Everything that begins must eventually end. This episode of beginnings and endings walks us both backwards and forwards as we take our final stroll down Wisteria Lane.
After losing both her husband and her business, Bree slowly begins the process of rebuilding her life, first by telling her friend Gabrielle a secret that could end their friendship, and then by starting up a romance with her much younger contractor Keith Watson. In the meantime, the Solises discover that their daughter Juanita was swapped at birth, and Lynette is visited by her old college roommate Renee Perry (Vanessa Williams), who later moves to the lane permanently. Bob and Lee find their way back to one another, and Susan and Mike's financial situations lead them to move to an apartment in the city and to take on jobs they don't want to endure through, whereas Paul Young, Mary Alice's widower, moves back to Wisteria Lane to wreak havoc.
Mary Alice Young, a seemingly perfect housewife commits suicide, fearing that a dark secret, involving her, her husband, and their son would be exposed.